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About the Microarray Research Laboratory (MARL)
Dr. Freshteh Toghrol, Senior Science Advisor
The Microarray Research Laboratory, under the Office of Pesticide Programs (OPP), conducts research in the genotoxicity of antimicrobials. The lab uses DNA microarray or Gene-chips®, a newly-developing technology and method, to identify toxicogenotoxic effects of various disinfectants on bacterial cell response. By using microarrays, the lab produces global gene expression profiles in pathogenic bacteria following exposure to antimicrobial agents, that are analyzed to help understand mechanisms involved in toxicity and resistance.