About EPA

About the National Center for Computational Toxicology (NCCT)

What We Do

The National Center for Computational Toxicology (NCCT) is the largest component of EPA's Computational Toxicology Research Program. It was established in 2005 to coordinate computational toxicology research on chemical screening and prioritization, informatics and systems modeling. NCCT is involved in the following areas:

  • Applies mathematical and advanced computer models to help assess chemical hazards and risks to human health and the environment.
  • Uses advances in informatics, high-throughput screening technologies and systems biology to develop robust and flexible computational tools that can screen the thousands of chemicals for potential toxicity.
  • Actively seeks partnerships with other government entities, private industries, academia and non-governmental organizations that provide chemicals, screening data, software and various chemical screening platforms to advance this research.
  • Works closely with EPA's offices, regions and other research labs.
  • Has staff with a wide-range of expertise including systems biology, engineering, toxicology, physics, statistics, biology, computational chemistry, bioinformatics, management and public affairs.

Learn more about EPA's Computational Toxicology Research

NCCT-Managed Research

Organization

Rusty Thomas, Director

Kevin Crofton, Acting Deputy Director