Laws & Regulations

Significant Guidance Documents by Office - OSA

This page lists significant guidance documents issued by the Office of the Science Advisor (OSA) or identified as a document for which OSA is the lead office. For every document, you may:

  • Comment on the document - Select "Comment" next to the relevant document to go to Regulations.gov, where you can view and comment on it. (Instructions for commenting.)
  • Learn more about the document and related EPA programs - Select "Learn More" to go to pages within the EPA Web site that give context to the document.

To browse the documents of other offices, select from the following list:

You also may :


Office of the Science Advisor (OSA)
Name (ID Number)
Comment
Learn More
Issuance Date
Date Added to This List
Most Recent Revision
Alpha2u-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male Rat (EPA/625/3-91/019F (NTIS PB92143668))
09/1991
08/23/2007
n/a
Assessment of Thyroid Follicular Cell Tumors (EPA/630/R-97/002)
03/1998
08/23/2007
n/a
Framework for Application of the Toxicity Equivalence Methodology for Polychlorinated Dioxins, Furans, and Biphenyls in Ecological Risk Assessment (EPA/100/R-08/004)
06/2008
07/15/2008
n/a
Framework for Cumulative Risk Assessment (EPA/600/P-02/001F)
03/2003
08/23/2007
n/a
Framework for Ecological Risk Assessment (EPA/630/R-92/001)
02/1992
08/23/2007
n/a
Framework for Metals Risk Assessment (EPA/120/R-07/001)
04/2007
07/24/2007
n/a
Generic Ecological Assessment Endpoints (GEAE) for Ecological Risk Assessment (EPA/630/P-02/004F)
10/2003
08/23/2007
n/a
Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants (EPA/630/P-03/003F)
11/2005
08/23/2007
n/a
Guidelines for Carcinogen Risk Assessment (EPA/630/P-03/001F)
03/2005
08/23/2007
n/a
Guidelines for Developmental Toxicity Risk Assessment (EPA/600/FR-91/001)
12/1991
08/23/2007
n/a
Guidelines for Ecological Risk Assessment (EPA/630/R-95/002F)
04/1998
08/23/2007
n/a
Guidelines for Exposure Assessment (EPA/600/Z-92/001)
05/1992
08/23/2007
n/a
Guidelines for Mutagenicity Risk Assessment (EPA/630/R-98/003)
09/1986
08/23/2007
n/a
Guidelines for Neurotoxicity Risk Assessment (EPA/630/R-95/001F)
04/1998
08/23/2007
n/a
Guidelines for Reproductive Toxicity Risk Assessment (EPA/630/R-96/009)
10/1996
08/23/2007
n/a
Guidelines for the Health Risk Assessment of Chemical Mixtures (EPA/630/R-98/002)
09/1986
08/23/2007
n/a
Guiding Principles for Monte Carlo Analysis (EPA/630/R-97/001)
03/1997
08/23/2007
n/a
Interim Procedures for Estimating Risks Associated with Exposures to Mixtures of Chlorinated Dibenzo-p-Dioxins and Dibenzofurans (CDDs and CDFs) and 1989 Update (EPA/625/3-89/016 (NTIS PB90145756))
03/1989
08/23/2007
n/a
Supplementary Guidance for Conducting Health Risk Assessment of Chemical Mixtures (EPA/630/R-00/002)
08/2000
08/23/2007
n/a

Instructions for Commenting on Documents at Regulations.gov

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  1. Click on the "Submit Comment" link found above the title of the document. (Note: If you do not see the icon next to "Add Comments," then the action is not currently accepting comments.)
  2. Fill out the form labeled "Submit a Comment" that appears.
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