Pesticide Registration

Study Profile Templates

The study profile templates below describe the layout and scope of information that should be contained within a study profile and can serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template.

Registrants are encouraged to submit completed study profile(s) and supporting data in electronic format in Microsoft Word. See electronic data submissions for additional information.

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Product Chemistry: Series 830

Study Profile Template Guideline
Number
Available
Formats
Version
Product Chemistry for Technical Grade of the Active Ingredient or Manufacturing Use Products (Group A and B data) N/A (7 pp, 148k, Word) May 2004
Product Chemistry for End Use Products N/A (6 pp, 110k, Word) May 2004

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Environmental Fate: Series 835

Study Profile Template Guideline
Number
Available
Formats
Version
Adsorption-Desorption of {Test Material} in Soil 835.1230 (12 pp, 427k, Word) May 2004
Hydrolysis of {Test Material} 835.2120 (9 pp, 388k, Word) May 2004
Phototransformation of {Test Material} in Water 835.2240 (11 pp, 188k, Word) May 2004
Phototransformation of {Test Material} on Soil 835.2410 (15 pp, 237k, Word) May 2004
Aerobic Biotransformation of {Test Material} in Soil 835.4100 (14 pp, 229k, Word) May 2004
Aerobic Biotransformation of {TGAI or EUP} in Water-Sediment System 835.4300 (11 pp, 228k, Word) May 2004
Anaerobic Biotransformation of {Test Material} in Water/Sediment System 835.4400 (11 pp, 229k, Word) May 2004
Terrestrial Field Dissipation of {Test Material} 835.6100 (20 pp, 452k, Word) May 2004

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Environmental Effects: Series 850

Study Profile Template Guideline
Number
Available
Formats
Version
Acute Toxicity Effects of {TAI or EUP} on Earthworms N/A (9 pp, 155k, Word) May 2004
Acute Toxicity of {TAI or EUP} to Freshwater Invertebrates - [Daphnia sp.] 850.1010 (9 pp, 175k, Word) May 2004
Acute Toxicity of {TAI or EUP} to Fish - [name of species] 850.1075 (10 pp, 192k, Word) May 2004
Chronic Toxicity of {TAI or EUP} to Fresh Water Invertebrates - [Daphnia sp.] 850.1300 (11 pp, 138k, Word) May 2004
Toxicity of {TAI or EUP} to Fish Early Life-Stage 850.1400 (10 pp, 170k, Word) May 2004
Acute Oral Toxicity of {TAI or EUP} to Avian Species - [name of species] 850.2100 (8 pp, 141k, Word) May 2004
Acute Dietary Toxicity of {TAI or EUP} to Avian Species - [name of species] 850.2200 (10 pp, 150k, Word) May 2004
Reproductive Effects of {TAI or EUP} on Avian Species - [name of species] 850.2300 (10 pp, 194k, Word) May 2004
Acute Toxicity of {TAI or EUP} to Terrestrial Vascular Plant - [name of species - seed germination-root elongation/seedling emergence/vegetative vigour] 850.4100
850.4150
(21 pp, 384k, Word) May 2004
Acute Toxicity of {TAI or EUP} to Aquatic Vascular Plants - [name of species] 850.4400 (11 pp, 159k, Word) May 2004
Acute Toxicity of {TAI or EUP} to Algae - [name of species] 850.5400 (12 pp, 320k, Word) May 2004

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Chemistry: Series 860 - Residue Chemistry Test Guidelines

Study Profile Template Guideline
Number
Available
Formats
Version
Study Profile Guidance N/A (5 pp, 45k, Word) July 2010
Nature of the Residue in Plants 860.1300 (7 pp, 127k, Word) July 2010
Nature of the Residue in Livestock 860.1300 (8 pp, 140k, Word) July 2010
Residue Analytical Method 860.1340 (6 pp, 110k, Word) July 2010
Storage Stability 860.1380 (5 pp, 60k, Word) July 2010
Water Fish and Irrigated Crops 860.1400 (12 pp, 215k, Word) July 2010
Food Handling 860.1460 (8 pp, 74k, Word) July 2010
Livestock Feeding Study 860.1480 (5 pp, 99k, Word) July 2010
Crop Field Trials 860.1500 (7 pp, 122k, Word) July 2010
Processed Food and Feed 860.1520 (5 pp, 72k, Word) July 2010
Confined Rotational Crops 860.1850 (9 pp, 137k, Word) July 2010
Multiresidue Method 860.1860 (3 pp, 50k, Word) July 2010
Field Rotational Crops 860.1900 (6 pp, 83k, Word) July 2010

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Toxicology: Series 870 - Health Effects Test Guidelines

Study Profile Template Guideline
Number
Available
Formats
Version
Acute Oral Toxicity - [species] 870.1100 (2 pp, 39k, Word) May 2004
Acute Dermal Toxicity - [species] 870.1200 (2 pp, 40k, Word) May 2004
Acute Inhalation Toxicity - [species] 870.1300 (2 pp, 46k, Word) May 2004
Primary Eye Irritation - [species] 870.2400 (3 pp, 47k, Word) May 2004
Primary Dermal Irritation - [species] 870.2500 (1 pp, 29k, Word) May 2004
Dermal Sensitization - [species] 870.2600 (4 pp, 85k, Word) May 2004
90-Day Oral Toxicity [dietary, gavage or drinking water] - [rodent species] 870.3100 (9 pp, 175k, Word) July 2010
90-Day Oral Toxicity [dietary, gavage or drinking water] - [non-rodent species] 870.3150 (8 pp, 173k, Word) July 2010
28-Day Dermal Toxicity - [species] 870.3200 (9 pp, 174k, Word) July 2010
90-Day Dermal Toxicity - [species] 870.3250 (9 pp, 174k, Word) July 2010
Subchronic Inhalation Toxicity - [species] 870.3465 (8 pp, 175k, Word) July 2010
Prenatal Developmental Toxicity Study - [rodent species] 870.3700 (8 pp, 143k, Word) July 2010
Prenatal Developmental Toxicity Study - [non-rodent species] 870.3700 (8 pp, 143k, Word) July 2010
Reproduction and Fertility Effects Study - [species] 870.3800 (12 pp, 238k, Word) July 2010
Chronic Toxicity [dietary, gavage, drinking water, dermal or inhalation] - [rodent species] 870.4100 (9 pp, 180k, Word) July 2010
Chronic Toxicity [feeding, water, dermal or inhalation] - [non-rodent species] 870.4100 (8 pp, 175k, Word) July 2010
Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 N/A (1 pp, 38k, Excel File) Feb 2012
Guidance and Examples for Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 N/A (1 pp, 43k, Excel File) Feb 2012
Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Mouse 870.4200 (9 pp, 181k, Word) July 2010
Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Rat 870.4200 (9 pp, 182k, Word) July 2010
Combined Chronic Toxicity/Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - [species] 870.4300 (9 pp, 184k, Word) July 2010
In Vitro Microbial Gene Mutation 870.5xxx (4 pp, 73k, Word) July 2010
In Vitro Mammalian Cells in Culture Gene Mutation Assay in [name cell type used] cells 870.5300 (4 pp, 83k, Word) July 2010
In Vitro Mammalian Cytogenetics (specify assay) or
In Vitro Sister Chromatid Exchange Assay in (name species/cell type)
870.5375
870.5900
(5 pp, 82k, Word) July 2010
In Vivo Mammalian Cytogenetics - Erythrocyte Micronucleus Assay in [name species] 870.5395 (4 pp, 86k, Word) July 2010
Other Genotoxicity: Unscheduled DNA Synthesis in Primary Rat Hepatocytes / Mammalian Cell Culture 870.5550 (4 pp, 51k, Word) July 2010
Neurotoxicity Screening Battery - Rat (Acute) 870.6200 (16 pp, 306k, Word) July 2010
Neurotoxicity Screening Battery - Rat (Subchronic) 870.6200 (16 pp, 281k, Word) July 2010
Developmental Neurotoxicity Study - Rat 870.6300 (29 pp, 615k, Word) July 2010
Metabolism Study - Rat 870.7485 (7 pp, 131k, Word) July 2010
Dermal Penetration 870.7600 (2 pp, 119k, Word) July 2010
Immunotoxicity 870.7800 (10 pp, 164k, Word) July 2010

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Occupational / Residential: Series 875 - Occupational and Residential Exposure Test Guidelines

Study Profile Template Guideline
Number
Available
Formats
Version
Use Pattern/Exposure Scenarios N/A (5 pp, 51k, Word) July 2010
Residential Post Application Passive Dosimetry 875.xxxx (13 pp, 313k, Word) July 2010
Mixer/Loader/Applicator Passive Dosimetry 875.1000 (4 pp, 372k, Word) July 2010
Agricultural Post Application Passive Dosimetry 875.2000 (14 pp, 327k, Word) July 2010
Dislodgeable Turf Residues 875.2100 (9 pp, 99k, Word) July 2010
Dislodgeable Foliar Residue 875.2100 (9 pp, 98k, Word) July 2010
Determination of Transferable Residue on Indoor Treated Surfaces 875.2300 (13 pp, 142k, Word) July 2010
Hand Press Residues 875.2300 (9 pp, 106k, Word) July 2010

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Endocrine: Series 890 - Endocrine Disruptor Screening Program Test Guidelines

Study Profile Template Guideline
Number
Available
Formats
Version
Amphibian Metamorphosis 890.1100 (25 pp, 247k, PDF)
(25 pp, 439k, Word)
September 2011
Androgen Receptor Binding (Rat Prostate) 890.1150 (14 pp, 255k, PDF)
(14 pp, 374k, Word)
October 2011
Aromatase (Human Recombinant) 890.1200 (12 pp, 178k, PDF)
(12 pp, 296k, Word)
July 2011
Estrogen Receptor Binding 890.1250 (15 pp, 255k, PDF)
(15 pp, 337k, Word)
October 2011
Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903) 890.1300 (10 pp, 156k, PDF)
(10 pp, 62k, Word)
August 2011
Fish Short-Term Reproduction 890.1350 (31 pp, 483k, PDF)
(31 pp, 155k, Word)
October 2011
Hershberger (Rat) 890.1400 (13 pp, 236k, PDF)
(13 pp, 238k, Word)
October 2011
Female Pubertal (Rat) 890.1450 (12 pp, 170k, PDF)
(12 pp, 251k, Word)
August 2011
Male Pubertal (Rat) 890.1500 (12 pp, 171k, PDF)
(12 pp, 268k, Word)
August 2011
Steroidogenesis (Human Cell Line – H295R) 890.1550 (9 pp, 121k, PDF)
(9 pp, 204k, Word)
July 2011
Uterotrophic (Rat) 890.1600 (13 pp, 190k, PDF)
(13 pp, 73k, Word)
September 2011

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More Information and Additional Resources

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